Invoke a Program Once then Delete from the Registry
This tweak allows you to set up a program that will be run once and then deleted so that it does not run again unless the entry is re-entered manually. The Runonce key does remain in the registry for reuse.
> [Start] [Run] [Regedit]

> Registry Key: HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\
Create the Key: Runonce

(The [Runonce] Key you create will remain in the registry for use with a new string value)
> Create Data Type: REG_SZ [String Value]

> Value Name: [Enter the Name of Program Executable]

> Value Data: [Enter the Path to the Program Executable]

> Exit Registry and Reboot

- srikanth dhanwada